Molecular Cell Biology



Department projects

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RNA editing and its functional consequences in the human brain
01/02/2013 - 31/12/2017
Under senare år har variationen i mRNA uttrycket visat sig ha en allt större betydelse för att skapa en nödvändig variation i vår proteinrepertoar. I vävnader som kräver stor proteinvariation så som hjärnan är det vanligt ...

Molecular Mechanisms of Fungal Pathogen Host Interactions
01/10/2013 - 30/09/2017
ImResFun shall provide state-of-the-art training in infectious disease research and medical immunology targeting the mostcommon human fungal pathogens, the opportunistic Candida species. The key objectives of ImResFun are: (i) to understandhow immune cells and infected organs res...

mRNA biogenesis in the eukaryotic cell
01/01/2013 - 31/12/2016
Alla celler i en organism innehåller likadan arvsmassa, men beroende på vilken uppgift cellen har använder den olika delar av arvsmassan (olika gener). I våra celler finns arvmassan förpackat i kromatin vilket består av långa DNA molekyler ...

Nutrient regulated gene expression in eukaryotic cells
01/01/2012 - 31/12/2015
Alla celler måste ta upp näringsämnen från sin omgivning för att överleva och dela sig. Vi studerar de mekanismer celler använder sig av för att fastställa tillgången på näringsämnen i sin växtmiljö, o...

Cellular functions of the Hsp70 chaperone machinery
01/01/2010 - 31/12/2013
Proteiner har invecklade tredimensionella strukturer som krävs för deras funktion i cellen. När proteiner veckas till sina aktiva strukturer i cellen krävs ofta assistans från specialiserade enzymer som kallas för Hsp70-chaperoner. Hsp70-chaperoner ...

Nutrient regulated gene expression II
01/01/2009 - 31/12/2011
Nutrient uptake is essential for life. We study the mechanisms of signal transduction that enable yeast cells to assess the availability of amino acids in their growth environment. The overall goal has been to use this model system to obtain precise and detailed mechanistic under...

Exploitation of an insect model to investigate nutrient controlled virulence of Candida albicans
01/01/2008 - 31/12/2010
Fungal infections are increasing and have serious consequences affecting the survival in the growing population of immuno-compromised patients, including those receiving chemotherapy and organ transplants, or infected with HIV. Candida albicans is the most common human fungal pat...

ATP-dependent Chromatin Remodelling Complexes in Transcription and other nuclear processes
01/01/2007 - 31/12/2009
Chromatin plays an important role in nuclear processes, as it constitutes a barrier for factors invovled in processes that need to gain access to DNA. Each cell has several proteins complexes that change the chromatin structure and play roles in gene regulation, replication, DNA ...


Last updated on 2017-08-05 at 13:55