Department of Biochemistry and Biophysics

Phone: +468162000
Fax: +468153679
Svante Arrhenius väg 16
106 91 Stockholm

Department projects

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The Swedish National Medical Bioinformatics Graduate School
01/01/2017 - 31/12/2019

In modern medical science, the bottleneck is often the computational analysis of high-throughput data. Scientists with a rigorous training in both medical and computational aspects are needed to design experiments appropriately and to fully take advantage of the generated data...

Enzymes: from the test tube into the cell
01/01/2016 - 31/12/2019

Enzymes are key players in all cellular processes in every living organism. In spite of a wealth of knowledge, the functions of enzymes are still incompletely understood. Numerous application in biotechnology are based on enzymology and approximately half of all pharmaceutical...

Network inference and analysis for understanding and predicting protein function
01/01/2016 - 31/12/2019

High-throughput biology (genomics, proteomics, transcriptomics, metabolomics, etc.) is producing massive amounts of biological data that in different ways can help us understand biology. A major challenge is to turn this Big Data into knowledge that generates novel biological ...

Membrane Protein Homeostasis and Production
01/01/2016 - 31/12/2019

Integral membrane proteins account for ~30% of all open reading frames in sequenced genomes, and they fulfil a wide range of central functions in the cell. However, our knowledge of this important class of proteins is still poor. Thus far, membrane protein biogenesis, quality ...

Cryo-EM analysis of the yeast heptameric post-translational translocon in a native membrane environment
01/07/2016 - 30/06/2019

One of the initial steps in the biogenesis of secretory proteins is translocation through the Sec61 translocon at the endoplasmic reticulum (ER). In yeast, two alternative translocation pathways lead to the translocon: the well characterized co-translational pathway and the mo...

Towards an effective monitoring of microplastics in the Baltic Sea (irPLAST)
01/01/2016 - 31/12/2018

Microplastics (MPs) are a newly recognized type of environmental pollution in aquatic systems. However, no monitoring of these contaminants in water column, sediments and biota is currently being conducted, mostly due to the lack of reliable, accessible and cost-e...

Intracellular protein transport in plants: signal peptides, molecular chaperones and proteolysis
01/01/2016 - 31/12/2018

Organelle biogenesis requires specific intracellular protein transport, sorting, processing and assembly machineries. Newly synthesized organellar proteins contain targeting signals that are recognized by organellar receptors and mediate import into the organelle. Molecular ch...

Proton transport in biological membranes
01/01/2015 - 31/12/2018
Biologiska membraner utgör gränsytor mellan levande organismer och omgivningen, omger celler och definierar utsträckningen för organeller inne i celler. Transport av stora och små molekyler samt joner över membraner spelar därför en centra...

Gene expression and mutation profiling in situ for personalized diagnostics, prognostics and treatment in prostate and breast cancer
01/01/2015 - 31/12/2018
Det har visats sig vara mycket värdefullt att karaktärisera cancertumörer genom att mäta deras genaktivitet, så kallad expressionsprofilering. Dessa expressionsprofiler säger något om tumörers egenskaper och kan användas för att...


Last updated on 2017-22-08 at 06:52