From the Structural Diversity of Nature to Efficient and Selective Catalysis


Project leader


Funding source

Swedish Research Council - Vetenskapsrådet (VR)


Project Details

Start date: 01/01/2010
End date: 31/12/2012
Funding: 2305000 SEK


Description

Asymmetric catalysis is the most powerful tool available for the production of chiral organic compounds. With an increasing amount of chiral drugs constantly being introduced on the market, the development of efficient and environmentally benign catalytic protocols for their production are of paramount importance. The general objective with this research program is to design and develop highly efficient and stereoselective catalysts which will facilitate important organic transformations. A vital instrument is the structural diversity of Nature, which provide us with a plethora of chiral building blocks for the preparation of these catalysts. The specific target areas which this research program will focus on are: 1) Development of efficient protocols for the asymmetric reduction of unsaturated organic compounds through the use of environmentally friendly iron, ruthenium and rhodium catalysts. 2) Mechanistic investigations on the function of these novel catalytic systems. 3) Development of chiral surfactants for environmentally benign catalysis - a conceptually novel approach for asymmetric catalysis

Last updated on 2017-31-03 at 12:58