Capsules in Flows


Funding source

Swedish Research Council - Vetenskapsrådet (VR)


Project Details

Start date: 01/01/2017
End date: 31/12/2020
Funding: 3800000 SEK


Description




The aim of this project is to study motion of capsules in microfluidic flows
using numerical tools. We want to develop a numerical
code to solve for capsules in microfluidic flows
in variety of situations. The code would be modular, easily maintainable
and released under GPL. The scientific aim is to use this code to
investigate sorting of capsules by their size and deformability.
The idea is to tune the code by close comparison with experiments
that are being done at Technical University Compaigne by the group of
Anne-Virgine Salsac. The code would not be merely limited to
zero Reynolds number microfluidics but would contains possibilities to
be generalized to inertial microfluidics and also to include density
and viscosity contrast between the inside and outside of the capsule.
We had earlier proposed a microfluidic device with potential to sort
capsules by their deformability. Now we want to realize such a device,
either from our earlier suggestion, or from a new design, by close
collaboration between experiments and numerical simulations.
Furthermore, by studying the inverse problem, we may be able to use the
same device to measure the elastic properties of large number of capsules.
Such a device may have significant industrial use. Furthermore, this is the
first step towards a future project to study sorting of
biological cells in microfluidic devices which, once developed, may
have far reaching consequence in biomedical research.



Last updated on 2017-06-10 at 07:43